reviewAIDSMay 4, 2016HYBRID OA

Effectiveness and safety of oral HIV preexposure prophylaxis for all populations

VAVirginia A. FonnerSLSarah L DalglishCECaitlin E. KennedyRBRachel BaggaleyKOKevin O’Reilly

Medical University of South Carolina

PubMed
Indexed incrossrefpubmed

Abstract

Objective

Preexposure prophylaxis (PrEP) offers a promising new approach to HIV prevention. This systematic review and meta-analysis evaluated the evidence for use of oral PrEP containing tenofovir disoproxil fumarate as an additional HIV prevention strategy in populations at substantial risk for HIV based on HIV acquisition, adverse events, drug resistance, sexual behavior, and reproductive health outcomes.

Design

Rigorous systematic review and meta-analysis.

Citation impact

1,017
total citations
FWCI
66.55
Percentile
100%
References
55
Citations per year

Authors

9

Topics & keywords

Topics
Keywords
  • Pre-exposure prophylaxis
  • Medicine
  • Adverse effect
  • Meta-analysis
  • Placebo
  • Risk compensation
  • Relative risk
  • Confidence interval
UN Sustainable Development Goals
  • Good health and well-being
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Funding