Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering
The University of Sydney · Brigham and Women's Hospital · +3 more institutions
Abstract
Tissue engineering holds great promise for regeneration and repair of diseased tissues, making the development of tissue engineering scaffolds a topic of great interest in biomedical research. Because of their biocompatibility and similarities to native extracellular matrix, hydrogels have emerged as leading candidates for engineered tissue scaffolds. However, precise control of hydrogel properties, such as porosity, remains a challenge. Traditional techniques for creating bulk porosity in polymers have demonstrated success in hydrogels for tissue engineering; however, often the conditions are incompatible with direct cell encapsulation. Emerging technologies have demonstrated the ability to control porosity…
Citation impact
- FWCI
- 15.10
- Percentile
- 100%
- References
- 110
Authors
7- NANasim Annabi
The University of Sydney
- JWJason W. Nichol
Brigham and Women's Hospital, Harvard University, Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology
- XZXia Zhong
The University of Sydney
- CJChengdong Ji
The University of Sydney
- STSandeep T. Koshy
Brigham and Women's Hospital, Harvard University, Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology
Topics & keywords
- Self-healing hydrogels
- Tissue engineering
- Porosity
- Biocompatibility
- Extracellular matrix
- Materials science
- Regeneration (biology)
- Nanotechnology
- Industry, innovation and infrastructure