articleJournal of Medicinal ChemistryOct 8, 2013Closed access

Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery

EAElizabeth A. IlardiEVEdon VitakuJTJón T. Njardarson

University of Arizona

PubMed
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Abstract

Among carbon, hydrogen, oxygen, and nitrogen, sulfur and fluorine are both leading constituents of the pharmaceuticals that comprise our medicinal history. In efforts to stimulate the minds of both the general public and expert scientist, statistics were collected from the trends associated with therapeutics spanning 12 disease categories (a total of 1969 drugs) from our new graphical montage compilation: disease focused pharmaceuticals posters. Each poster is a vibrant display of a collection of pharmaceuticals (including structural image, Food and Drug Administration (FDA) approval date, international nonproprietary name (INN), initial market name, and a color-coded subclass of function) organized…

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1,563
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19.17
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100%
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51
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Authors

3

Topics & keywords

Topics
Keywords
  • Food and drug administration
  • Drug discovery
  • Chemistry
  • Drug
  • Sulfur
  • Pharmacology
  • Medicine
  • Organic chemistry
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