articlePLoS ONEMay 26, 2016GOLD OA

Intestinal Microbiota Is Influenced by Gender and Body Mass Index

CHCarmen HaroOAOriol Alberto Rangel-ZúñigaJFJuan F. Alcalá‐DíazFGFrancisco Gómez-DelgadoPPPablo Pérez‐Martínez

Instituto de Salud Carlos III · Instituto Maimónides de Investigación Biomédica de Córdoba · +4 more institutions

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Abstract

Intestinal microbiota changes are associated with the development of obesity. However, studies in humans have generated conflicting results due to high inter-individual heterogeneity in terms of diet, age, and hormonal factors, and the largely unexplored influence of gender. In this work, we aimed to identify differential gut microbiota signatures associated with obesity, as a function of gender and changes in body mass index (BMI). Differences in the bacterial community structure were analyzed by 16S sequencing in 39 men and 36 post-menopausal women, who had similar dietary background, matched by age and stratified according to the BMI. We observed that the abundance of the Bacteroides genus was lower in men…

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Topics & keywords

Topics
Keywords
  • Veillonella
  • Body mass index
  • Obesity
  • Biology
  • Gut flora
  • Bacteroides
  • Prevotella
  • Microbiome
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