Assessing the Gold Standard — Lessons from the History of RCTs

Bothwell, Laura E.; Greene, Jeremy A.; Podolsky, Scott H.; Jones, David S.

doi:10.1056/nejmms1604593

articleNew England Journal of MedicineJun 2, 2016Closed access

Assessing the Gold Standard — Lessons from the History of RCTs

LELaura E. Bothwell JAJeremy A. Greene SHScott H. Podolsky DSDavid S. Jones

Pharmac · Brigham and Women's Hospital · +4 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

Randomized, controlled trials have become the gold standard of medical knowledge. Yet their scientific and political history offers lessons about the complexity of medicine and disease and the economic and political forces shaping the production and circulation of knowledge.

Citation impact

648

total citations

FWCI: 60.15
Percentile: 100%
References: 54

Citations per year

Authors

LE
Laura E. BothwellCorresponding
Pharmac, Brigham and Women's Hospital, Harvard University
JA
Jeremy A. Greene
Johns Hopkins Medicine, Johns Hopkins University
SH
Scott H. Podolsky
Harvard Global Health Institute, Harvard University
DS
David S. Jones
Harvard Global Health Institute, Harvard University

Topics & keywords

Topics

Health and Medical Research Impacts99%
Health Systems, Economic Evaluations, Quality of Life98%
Healthcare cost, quality, practices97%

Keywords

Gold standard (test)
Politics
Randomized controlled trial
Circulation (fluid dynamics)
Political science
Medicine
Engineering ethics
Engineering

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