EAACI Molecular Allergology User's Guide
Charité - Universitätsmedizin Berlin · Aarhus University Hospital · +59 more institutions
Abstract
The availability of allergen molecules ('components') from several protein families has advanced our understanding of immunoglobulin E (IgE)-mediated responses and enabled 'component-resolved diagnosis' (CRD). The European Academy of Allergy and Clinical Immunology (EAACI) Molecular Allergology User's Guide (MAUG) provides comprehensive information on important allergens and describes the diagnostic options using CRD. Part A of the EAACI MAUG introduces allergen molecules, families, composition of extracts, databases, and diagnostic IgE, skin, and basophil tests. Singleplex and multiplex IgE assays with components improve both sensitivity for low-abundance allergens and analytical specificity; IgE to…
Citation impact
- FWCI
- 62.78
- Percentile
- 100%
- References
- 846
Authors
65Topics & keywords
- Medicine
- Immunoglobulin E
- Allergy
- Basophil activation
- Immunology
- Plant lipid transfer proteins
- Allergen
- Dander
Funding
- GGlaxoSmithKline
- SSanofi
- MJMead Johnson Nutrition
- ECEuropean Commission
- DFDeutsche Forschungsgemeinschaft
- BFBundesministerium für Bildung und Forschung
- ASAustrian Science Fund
- APAstellas Pharma
- EAEuropean Academy of Allergy and Clinical Immunology
- NNestec
- SASanofi Australia
- NINational Institutes of Health
- MRMedical Research Council
- NHNational Health and Medical Research Council
- IDInstituto de Salud Carlos III
- NINational Institute of Allergy and Infectious Diseases