Self-Healing Conductive Injectable Hydrogels with Antibacterial Activity as Cell Delivery Carrier for Cardiac Cell Therapy
Xi'an Jiaotong University · University of Michigan–Ann Arbor
Abstract
Cell therapy is a promising strategy to regenerate cardiac tissue for myocardial infarction. Injectable hydrogels with conductivity and self-healing ability are highly desirable as cell delivery vehicles for cardiac regeneration. Here, we developed self-healable conductive injectable hydrogels based on chitosan-graft-aniline tetramer (CS-AT) and dibenzaldehyde-terminated poly(ethylene glycol) (PEG-DA) as cell delivery vehicles for myocardial infarction. Self-healed electroactive hydrogels were obtained after mixing CS-AT and PEG-DA solutions at physiological conditions. Rapid self-healing behavior was investigated by rheometer. Swelling behavior, morphology, mechanical strength, electrochemistry, conductivity,…
Citation impact
- FWCI
- 58.23
- Percentile
- 100%
- References
- 74
Authors
4Topics & keywords
- Self-healing hydrogels
- Materials science
- Biocompatibility
- Biomedical engineering
- Ethylene glycol
- Tissue engineering
- Cell encapsulation
- C2C12