articleAnnals of Internal MedicineJun 20, 2016Closed access

Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus

The University of Texas Health Science Center at San Antonio · Audie L. Murphy Memorial VA Hospital · +2 more institutions

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Abstract

Background

The metabolic defects of nonalcoholic steatohepatitis (NASH) and prediabetes or type 2 diabetes mellitus (T2DM) seem to be specifically targeted by pioglitazone. However, information about its long-term use in this population is limited.

Objective

To determine the efficacy and safety of long-term pioglitazone treatment in patients with NASH and prediabetes or T2DM.

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Funding