High‐Strength and High‐Toughness Double‐Cross‐Linked Cellulose Hydrogels: A New Strategy Using Sequential Chemical and Physical Cross‐Linking
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Abstract
Polysaccharide‐based hydrogels have multiple advantages because of their inherent biocompatibility, biodegradability, and non‐toxicic properties. The feasibility of using polysaccharide‐based hydrogels could be improved if they could simultaneously fulfill the mechanical property and cell compatibility requirements for practical applications. Herein, the construction of double‐cross‐linked (DC) cellulose hydrogels is described using sequential chemical and physical cross‐linking, resulting in DC cellulose hydrogels that are mechanically superior to single‐cross‐linked cellulose hydrogels. The formation and spatial distribution of chemically cross‐linked domains and physically cross‐linked domains within the DC…
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537
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6Topics & keywords
Topics
Keywords
- Self-healing hydrogels
- Cellulose
- Materials science
- Epichlorohydrin
- Toughness
- Biocompatibility
- Chemical engineering
- Composite material
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