articleBMJJun 22, 2016HYBRID OA

External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges

RDRichard D RileyJEJoie EnsorKIKym I E SnellTPThomas P. A. DebrayDADoug Altman

Keele University · University of Birmingham · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Access to big datasets from e-health records and individual participant data (IPD) meta-analysis is signalling a new advent of external validation studies for clinical prediction models. In this article, the authors illustrate novel opportunities for external validation in big, combined datasets, while drawing attention to methodological challenges and reporting issues.

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554
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Authors

7

Topics & keywords

Topics
Keywords
  • Computer science
  • Big data
  • Data science
  • Health records
  • Data mining
  • Health care
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