reviewChemical ReviewsJul 27, 2016GREEN OA

Mn-, Fe-, and Co-Catalyzed Radical Hydrofunctionalizations of Olefins

SWSteven W. M. CrossleyCOCarla ObradorsRMRuben M. MartinezRARyan A. Shenvi

Scripps Research Institute

PubMed
Indexed incrossrefpubmed

Abstract

Cofactor-mimetic aerobic oxidation has conceptually merged with catalysis of syngas reactions to form a wide range of Markovnikov-selective olefin radical hydrofunctionalizations. We cover the development of the field and review contributions to reaction invention, mechanism, and application to complex molecule synthesis. We also provide a mechanistic framework for understanding this compendium of radical reactions.

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1,077
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24.62
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100%
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469
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Authors

4

Topics & keywords

Topics
Keywords
  • Chemistry
  • Catalysis
  • Olefin fiber
  • Combinatorial chemistry
  • Compendium
  • Organic chemistry
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