Electrochemical Methods for the Analysis of Clinically Relevant Biomolecules

Rapid progress in identifying biomarkers that are hallmarks of disease has increased demand for high-performance detection technologies. Implementation of electrochemical methods in clinical analysis may provide an effective answer to the growing need for rapid, specific, inexpensive, and fully automated means of biomarker analysis. This Review summarizes advances from the past 5 years in the development of electrochemical sensors for clinically relevant biomolecules, including small molecules, nucleic acids, and proteins. Various sensing strategies are assessed according to their potential for reaching relevant limits of sensitivity, specificity, and degrees of multiplexing. Furthermore, we address the…

• GC
  Genome Canada
• OM
  Ontario Ministry of Research, Innovation and Science
• CI
  Canadian Institutes of Health Research
• CC
  Canadian Cancer Society Research Institute

  Award: 702414
• NS
  Natural Sciences and Engineering Research Council of Canada