Neural mechanisms of transient neocortical beta rhythms: Converging evidence from humans, computational modeling, monkeys, and mice

Sherman, Maxwell A.; Lee, Shane; Law, Robert; Haegens, Saskia; Thorn, Catherine A.; Hämäläinen, Matti; Moore, Christopher I.; Jones, Stephanie R.

doi:10.1073/pnas.1604135113

articleProceedings of the National Academy of SciencesJul 28, 2016BRONZE OA

Neural mechanisms of transient neocortical beta rhythms: Converging evidence from humans, computational modeling, monkeys, and mice

MAMaxwell A. Sherman SLShane Lee RLRobert Law SHSaskia Haegens CACatherine A. Thorn

Brown University · Nathan Kline Institute for Psychiatric Research · +6 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

Human neocortical 15-29-Hz beta oscillations are strong predictors of perceptual and motor performance. However, the mechanistic origin of beta in vivo is unknown, hindering understanding of its functional role. Combining human magnetoencephalography (MEG), computational modeling, and laminar recordings in animals, we present a new theory that accounts for the origin of spontaneous neocortical beta. In our MEG data, spontaneous beta activity from somatosensory and frontal cortex emerged as noncontinuous beta events typically lasting

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Topics & keywords

Topics

Keywords

Neuroscience
Magnetoencephalography
BETA (programming language)
Somatosensory system
Neocortex
Beta Rhythm
Excitatory postsynaptic potential
Mechanism (biology)

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