articleEnvironmental Science & TechnologyJul 20, 2016Closed access

Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer ( Brachionus koreanus )

CJChang-Bum JeongEWEun-Ji WonHKHye-Min KangMLMin‐Chul LeeDHDae-Sik Hwang

Hanyang University · Sungkyunkwan University · +7 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

In this study, we evaluated accumulation and adverse effects of ingestion of microplastics in the monogonont rotifer (Brachionus koreanus). The dependence of microplastic toxicity on particle size was investigated by measuring several in vivo end points and studying the ingestion and egestion using 0.05-, 0.5-, and 6-μm nonfunctionalized polystyrene microbeads. To identify the defense mechanisms activated in response to microplastic exposure, the activities of several antioxidant-related enzymes and the phosphorylation status of mitogen-activated protein kinases (MAPKs) were determined. Exposure to polystyrene microbeads of all sizes led to significant size-dependent effects, including reduced growth rate,…

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1,200
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10

Topics & keywords

Topics
Keywords
  • Rotifer
  • Microplastics
  • Toxicity
  • Biology
  • Brachionus
  • Oxidative stress
  • Ingestion
  • Brachionus calyciflorus
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