Saliva in the diagnosis of diseases
State Key Laboratory of Oral Diseases · Sichuan University · +1 more institution
Abstract
Saliva is secreted from the salivary glands and has multiple functions, including mouth cleaning and protection, antibacterial effects and digestion. With the rapid advancement in salivaomics, saliva is well recognized as a pool of biological markers. Saliva, as a non-invasive and safe source, could be a substitute for blood in the diagnosis and prognosis of diseases. This review summarizes the latest advancements in saliva-related studies and addresses the potential value of saliva in the early diagnosis of oral diseases, such as dental caries and periodontal disease, as well as cancer, diabetes and other systemic disorders. Saliva biomarkers range from changes in the biochemical indices of DNA, RNA and…
Citation impact
- FWCI
- 13.44
- Percentile
- 100%
- References
- 57
Authors
7- CZChen-Zi ZhangCorresponding
State Key Laboratory of Oral Diseases, Sichuan University
- XCXingqun Cheng
State Key Laboratory of Oral Diseases, Sichuan University
- JLJi-Yao Li
Sichuan University, State Key Laboratory of Oral Diseases
- PZPing Zhang
State Key Laboratory of Oral Diseases, Sichuan University
- PYPing Yi
Sichuan University, West China Hospital of Sichuan University
Topics & keywords
- Saliva
- Medicine
- Disease
- Immunology
- Pathology
- Internal medicine