Discerning the Chemistry in Individual Organelles with Small‐Molecule Fluorescent Probes
Agency for Science, Technology and Research · National University of Singapore · +4 more institutions
Abstract
Principle has it that even the most advanced super-resolution microscope would be futile in providing biological insight into subcellular matrices without well-designed fluorescent tags/probes. Developments in biology have increasingly been boosted by advances of chemistry, with one prominent example being small-molecule fluorescent probes that not only allow cellular-level imaging, but also subcellular imaging. A majority, if not all, of the chemical/biological events take place inside cellular organelles, and researchers have been shifting their attention towards these substructures with the help of fluorescence techniques. This Review summarizes the existing fluorescent probes that target…
Citation impact
- FWCI
- 61.42
- Percentile
- 100%
- References
- 412
Authors
5- WXWanghong Xu
Agency for Science, Technology and Research, National University of Singapore, Hunan University, Singapore Bioimaging Consortium, State Key Laboratory of Chemobiosensing and Chemometrics, Stanford University
- ZZZebing Zeng
Hunan University, State Key Laboratory of Chemobiosensing and Chemometrics
- JJJian‐Hui JiangCorresponding
Hunan University, State Key Laboratory of Chemobiosensing and Chemometrics
- YCYoung‐Tae ChangCorresponding
Agency for Science, Technology and Research, National University of Singapore, Singapore Bioimaging Consortium
- LYLin YuanCorresponding
Hunan University, State Key Laboratory of Chemobiosensing and Chemometrics
Topics & keywords
- Organelle
- Fluorescence
- Nanotechnology
- Chemical biology
- Fluorescence microscope
- Resolution (logic)
- Chemistry
- Biophysics