Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus

The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel…

• A
  Amgen
• EL
  Eli Lilly and Company
• A
  AstraZeneca
• AP
  Alexion Pharmaceuticals
• D
  Danone
• MU
  McMaster University
• RH
  Radius Health
• AH
  AgNovos Healthcare
• S
  Servier
• I
  Ipsen
• NI
  National Institute of Arthritis and Musculoskeletal and Skin Diseases