Cancer‐Cell‐Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors
Shanghai Institute of Materia Medica · Shenyang Pharmaceutical University · +1 more institution
Abstract
A unique biomimetic drug-delivery system composed of 4T1-breast-cancer-cell membranes and paclitaxel-loaded polymeric nanoparticles (PPNs) (cell-membrane-coated PPNs), demonstrates superior interactions to its source tumor cells and elongated blood circulation, and displays highly cell-specific targeting of the homotypic primary tumor and metastases, with successful inhibition of the growth and lung metastasis of the breast cancer cells. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting…
Citation impact
- FWCI
- 21.31
- Percentile
- 100%
- References
- 39
Authors
11- HSHuiping Sun
Shanghai Institute of Materia Medica, Shenyang Pharmaceutical University, Chinese Academy of Sciences
- JSJinghan Su
Chinese Academy of Sciences, Shanghai Institute of Materia Medica
- QMQingshuo Meng
Chinese Academy of Sciences, Shanghai Institute of Materia Medica
- QYQi Yin
Chinese Academy of Sciences, Shanghai Institute of Materia Medica
- LCLingli Chen
Chinese Academy of Sciences, Shanghai Institute of Materia Medica
Topics & keywords
- Materials science
- Paclitaxel
- Cancer cell
- Drug delivery
- Cell
- Cancer research
- Cancer
- Circulating tumor cell
- Good health and well-being