Fluorescent Probes for Sensing and Imaging within Specific Cellular Organelles

Fluorescent probes have become powerful tools in biosensing and bioimaging because of their high sensitivity, specificity, fast response, and technical simplicity. In the last decades, researchers have made remarkable progress in developing fluorescent probes that respond to changes in microenvironments (e.g., pH, viscosity, and polarity) or quantities of biomolecules of interest (e.g., ions, reactive oxygen species, and enzymes). All of these analytes are specialized to carry out vital functions and are linked to serious disorders in distinct subcellular organelles. Each of these organelles plays a specific and indispensable role in cellular processes. For example, the nucleus regulates gene expression,…

• NN
  National Natural Science Foundation of China

  Awards: 21421005, 21406028, 21136002, 21376037, 21422601
• MO
  Ministry of Science and Technology of the People's Republic of China

  Awards: 2013AA020202, 2013CB733702
• PF
  Program for New Century Excellent Talents in University

  Award: NCET-12-0080