Plasma tau in Alzheimer disease

Mattsson, Niklas; Zetterberg, Henrik; Janelidze, Shorena; Insel, Philip S.; Andréasson, Ulf; Stomrud, Erik; Palmqvist, Sebastian; Baker, David; Hehir, Cristina A. Tan; Jeromin, Andreas; Hanlon, David; Song, Linan; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael W.; Hansson, Oskar; Blennow, Kaj

doi:10.1212/wnl.0000000000003246

articleNeurologyOct 1, 2016BRONZE OA

Plasma tau in Alzheimer disease

NMNiklas Mattsson HZHenrik Zetterberg SJShorena Janelidze PSPhilip S. Insel UAUlf Andréasson

University of California, San Francisco · Quanterix (United States) · +4 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

Objective

To test whether plasma tau is altered in Alzheimer disease (AD) and whether it is related to changes in cognition, CSF biomarkers of AD pathology (including β-amyloid [Aβ] and tau), brain atrophy, and brain metabolism.

Methods

fluorodeoxyglucose-PET, and cognition.

Citation impact

510

total citations

FWCI: 26.08
Percentile: 100%
References: 25

Citations per year

Authors

NM
Niklas MattssonCorresponding
University of California, San Francisco, Quanterix (United States), GE Global Research (United States), Janssen (United States), University of Pennsylvania, University of Gothenburg
HZ
Henrik Zetterberg
University of California, San Francisco, Quanterix (United States), GE Global Research (United States), Janssen (United States), University of Pennsylvania, University of Gothenburg
SJ
Shorena Janelidze
University of California, San Francisco, Quanterix (United States), GE Global Research (United States), Janssen (United States), University of Pennsylvania, University of Gothenburg
PS
Philip S. Insel
University of California, San Francisco, Quanterix (United States), GE Global Research (United States), Janssen (United States), University of Pennsylvania, University of Gothenburg
UA
Ulf Andréasson
University of California, San Francisco, Quanterix (United States), GE Global Research (United States), Janssen (United States), University of Pennsylvania, University of Gothenburg

Topics & keywords

Topics

Alzheimer's disease research and treatments82%
Dementia and Cognitive Impairment Research17%
Neurological Disease Mechanisms and Treatments0%

Keywords

Alzheimer's Disease Neuroimaging Initiative
Dementia
Atrophy
Psychology
Neuroimaging
Biomarker
Alzheimer's disease
Cognition

UN Sustainable Development Goals

Good health and well-being

No related works found for this paper.

Funding

UD
U.S. Department of Defense
Award: AG024904
UD
U.S. Department of Veterans Affairs
EL
Eli Lilly and Company
Award: AG024904
P
Pfizer
Award: AG024904
S
Sanofi
B
Biogen
Award: AG024904
UO
University of Pennsylvania
S
Synarc
HU
Harvard University
D
Danone
GU
Göteborgs Universitet
NI
National Institutes of Health
Award: AG024904
UO
University of California, Los Angeles
NI
National Institute on Aging
Award: AG024904