Two-photon excitation nanoparticles for photodynamic therapy
Chimie Biologique pour le Vivant · Nanjing University · +1 more institution
Abstract
) which can kill cancer cells. The long-wavelength light used to excite TPE NPs allows for deeper tissue penetration to achieve efficient PDT of deep-seated tumors. Moreover, TPE nanoparticles normally have large two-photon absorption (TPA) cross-sections, which hold great potential as efficient two-photon donors in PDT. In this review, we will summarize the recent advances made in the development of TPE nanoparticles for cancer PDT. Five different TPE nanoparticles, including quantum dots (QDs), carbon nanomaterials, silica nanoparticles, gold nanomaterials, and polymer nanoparticles, are summarized in detail, and the existing challenges as well as the future perspectives are also discussed.
Citation impact
- FWCI
- 32.89
- Percentile
- 100%
- References
- 179
Authors
5- YSYizhong Shen
Chimie Biologique pour le Vivant, Nanjing University
- AJAdam J. Shuhendler
University of Ottawa
- DYDeju YeCorresponding
Chimie Biologique pour le Vivant, Nanjing University
- JXJing‐Juan Xu
Chimie Biologique pour le Vivant, Nanjing University
- HCHong‐Yuan ChenCorresponding
Chimie Biologique pour le Vivant, Nanjing University
Topics & keywords
- Photodynamic therapy
- Excitation
- Two-photon excitation microscopy
- Nanoparticle
- Photon
- Nanotechnology
- Chemistry
- Materials science
Funding
- CRCanada Research Chairs
- NNNational Natural Science Foundation of ChinaAwards: 21505070, 21372115, 21632008, 21327902
- MOMinistry of Science and Technology of the People's Republic of China
- NSNatural Science Foundation of Jiangsu ProvinceAward: BK20150567
- NSNatural Sciences and Engineering Research Council of Canada