circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations

It has been known that circular RNAs are widely expressed in human tissues and cells, and play important regulatory roles in physiological or pathological processes. However, there is lack of comprehensively annotated human circular RNAs database. In this study we established a circRNA database, named as circRNADb, containing 32,914 human exonic circRNAs carefully selected from diversified sources. The detailed information of the circRNA, including genomic information, exon splicing, genome sequence, internal ribosome entry site (IRES), open reading frame (ORF) and references were provided in circRNADb. In addition, circRNAs were found to be able to encode proteins, which have not been reported in any species.…

• NN
  National Natural Science Foundation of China

  Awards: 81270700, 31471403, 61571223, 61171191
• GO
  Government of Jiangsu Province

  Award: SWYY-021
• NK
  National Key Research and Development Program of China

  Awards: 2016YFA0503300, 2013CB911400
• SR
  Specialized Research Fund for the Doctoral Program of Higher Education of China