articleNucleic Acids ResearchOct 12, 2016GOLD OA

PlantTFDB 4.0: toward a central hub for transcription factors and regulatory interactions in plants

State Key Laboratory of Plant Genomics · State Key Laboratory of Protein and Plant Gene Research · +3 more institutions

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Abstract

With the goal of providing a comprehensive, high-quality resource for both plant transcription factors (TFs) and their regulatory interactions with target genes, we upgraded plant TF database PlantTFDB to version 4.0 (http://planttfdb.cbi.pku.edu.cn/). In the new version, we identified 320 370 TFs from 165 species, presenting a more comprehensive genomic TF repertoires of green plants. Besides updating the pre-existing abundant functional and evolutionary annotation for identified TFs, we generated three new types of annotation which provide more directly clues to investigate functional mechanisms underlying: (i) a set of high-quality, non-redundant TF binding motifs derived from experiments; (ii) multiple…

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