Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
University of Pennsylvania · Harvard University · +4 more institutions
Indexed incrossrefpubmed
Abstract
Epigenetic landscape. These data indicate that epigenetic fate inflexibility may limit current immunotherapies.
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1,278
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Authors
19Topics & keywords
Topics
Keywords
- Blockade
- Durability
- Epigenetics
- Stability (learning theory)
- Chemistry
- Computer science
- Receptor
- Gene
UN Sustainable Development Goals
- Zero hunger
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