Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms

Due to their unique physicochemical properties, graphene-family nanomaterials (GFNs) are widely used in many fields, especially in biomedical applications. Currently, many studies have investigated the biocompatibility and toxicity of GFNs in vivo and in intro. Generally, GFNs may exert different degrees of toxicity in animals or cell models by following with different administration routes and penetrating through physiological barriers, subsequently being distributed in tissues or located in cells, eventually being excreted out of the bodies. This review collects studies on the toxic effects of GFNs in several organs and cell models. We also point out that various factors determine the toxicity of GFNs…

• NN
  National Natural Science Foundation of China

  Awards: 2015A030313299, 51172283, 81550011, 81400557
• NS
  Natural Science Foundation of Guangdong Province

  Award: 2015A030313299
• GM
  Guangdong Medical Research Foundation

  Award: A2016360