Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
Beth Israel Deaconess Medical Center
Indexed incrossrefpubmed
Abstract
The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.
Citation impact
1,347
total citations
- FWCI
- 54.24
- Percentile
- 100%
- References
- 72
Citations per year
Authors
1Topics & keywords
Topics
Keywords
- Medicine
- Signal transduction
- Immune system
- Alternative complement pathway
- Immune tolerance
- Cancer research
- Cell biology
- Computational biology
UN Sustainable Development Goals
- Good health and well-being
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