Abstract

Regeneration and tissue repair processes consist of a sequence of molecular and cellular events which occur after the onset of a tissue lesion in order to restore the damaged tissue. The exsudative, proliferative, and extracellular matrix remodeling phases are sequential events that occur through the integration of dynamic processes involving soluble mediators, blood cells, and parenchymal cells. Exsudative phenomena that take place after injury contribute to the development of tissue edema. The proliferative stage seeks to reduce the area of tissue injury by contracting myofibroblasts and fibroplasia. At this stage, angiogenesis and reepithelialization processes can still be observed. Endothelial cells are…

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1,566
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Authors

4

Topics & keywords

Keywords
  • Wound healing
  • Extracellular matrix
  • Regeneration (biology)
  • Angiogenesis
  • Pathology
  • Parenchyma
  • Mesenchymal stem cell
  • Tissue remodeling
UN Sustainable Development Goals
  • Good health and well-being
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