Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences
University College London · University of Reading
Abstract
Advances in the technologies and informatics used to generate and process large biological data sets (omics data) are promoting a critical shift in the study of biomedical sciences. While genomics, transcriptomics and proteinomics, coupled with bioinformatics and biostatistics, are gaining momentum, they are still, for the most part, assessed individually with distinct approaches generating monothematic rather than integrated knowledge. As other areas of biomedical sciences, including metabolomics, epigenomics and pharmacogenomics, are moving towards the omics scale, we are witnessing the rise of inter-disciplinary data integration strategies to support a better understanding of biological systems and…
Citation impact
- FWCI
- 17.76
- Percentile
- 100%
- References
- 154
Authors
7Topics & keywords
- Data science
- Omics
- Pharmacogenomics
- Genomics
- Data integration
- Reductionism
- Informatics
- Proteomics
Funding
- MJMichael J. Fox Foundation for Parkinson's Research
- WWellcomeAwards: 089698/Z/09/Z, 091673/Z/10/Z
- NINational Institute on Handicapped Research
- PUParkinson's UK
- UCUniversity College London
- RTRosetrees Trust
- UOUniversity of Sheffield
- MRMedical Research CouncilAwards: MR/L010933/1, MR/L010933/1, MR/N026004/1, WT089698, MR/N026004/1