articleCirculationSep 28, 2016BRONZE OA

Predicting the 10-Year Risks of Atherosclerotic Cardiovascular Disease in Chinese Population

Shenzhen University · Chinese Academy of Medical Sciences & Peking Union Medical College · +6 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Background

The accurate assessment of individual risk can be of great value to guiding and facilitating the prevention of atherosclerotic cardiovascular disease (ASCVD). However, prediction models in common use were formulated primarily in white populations. The China-PAR project (Prediction for ASCVD Risk in China) is aimed at developing and validating 10-year risk prediction equations for ASCVD from 4 contemporary Chinese cohorts.

Methods

Two prospective studies followed up together with a unified protocol were used as the derivation cohort to develop 10-year ASCVD risk equations in 21 320 Chinese participants. The external validation was evaluated in 2 independent Chinese cohorts with 14 123 and 70 838 participants. Furthermore, model performance was compared with the Pooled Cohort Equations reported in the American College of Cardiology/American Heart Association guideline.

Citation impact

649
total citations
FWCI
19.72
Percentile
100%
References
41
Citations per year

Authors

16

Topics & keywords

Keywords
  • Medicine
  • Atherosclerotic cardiovascular disease
  • Disease
  • Population
  • Cardiology
  • Internal medicine
  • Environmental health
UN Sustainable Development Goals
  • Good health and well-being
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