RNAi Efficiency, Systemic Properties, and Novel Delivery Methods for Pest Insect Control: What We Know So Far

In recent years, the research on the potential of using RNA interference (RNAi) to suppress crop pests has made an outstanding growth. However, given the variability of RNAi efficiency that is observed in many insects, the development of novel approaches toward insect pest management using RNAi requires first to unravel factors behind the efficiency of dsRNA-mediated gene silencing. In this review, we explore essential implications and possibilities to increase RNAi efficiency by delivery of dsRNA through non-transformative methods. We discuss factors influencing the RNAi mechanism in insects and systemic properties of dsRNA. Finally, novel strategies to deliver dsRNA are discussed, including delivery by…

• CD
  Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
• FW
  Fonds Wetenschappelijk Onderzoek
• AV
  Agentschap voor Innovatie door Wetenschap en Technologie
• CN
  Conselho Nacional de Desenvolvimento Científico e Tecnológico
• UG
  Universiteit Gent
• VR
  Vlaamse regering
• BO
  Bijzonder Onderzoeksfonds UGent