reviewClinical Microbiology ReviewsNov 18, 2016BRONZE OA

From Q Fever to Coxiella burnetii Infection: a Paradigm Change

CECarole EldinCMCléa MelenotteOMOleg MediannikovÉGÉric GhigoMMMatthieu Million

Centre National de la Recherche Scientifique · Inserm · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Coxiella burnetii is the agent of Q fever, or "query fever," a zoonosis first described in Australia in 1937. Since this first description, knowledge about this pathogen and its associated infections has increased dramatically. We review here all the progress made over the last 20 years on this topic. C. burnetii is classically a strict intracellular, Gram-negative bacterium. However, a major step in the characterization of this pathogen was achieved by the establishment of its axenic culture. C. burnetii infects a wide range of animals, from arthropods to humans. The genetic determinants of virulence are now better known, thanks to the achievement of determining the genome sequences of several strains of this…

Citation impact

986
total citations
FWCI
55.04
Percentile
100%
References
722
Citations per year

Authors

9

Topics & keywords

Topics
Keywords
  • Q fever
  • Coxiella burnetii
  • Rickettsiosis
  • Rickettsiales
  • Virology
  • Biology
  • Immunology
  • Microbiology
UN Sustainable Development Goals
  • Good health and well-being
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