articleNature MedicineNov 21, 2016Closed access

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

SCShira CramerASAchinto SahaJLJinyun LiuSTSurendar TadiSTStefano Tiziani

The University of Texas at Austin · The University of Texas MD Anderson Cancer Center · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

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534
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26.10
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100%
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60
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Authors

16

Topics & keywords

Topics
Keywords
  • Reactive oxygen species
  • Glutathione
  • Oxidative stress
  • Cancer research
  • Cancer cell
  • Intracellular
  • Extracellular
  • Biology
UN Sustainable Development Goals
  • Good health and well-being
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