Cancer Cell Membrane–Biomimetic Nanoparticles for Homologous-Targeting Dual-Modal Imaging and Photothermal Therapy
Chinese Academy of Sciences · Shenzhen Institutes of Advanced Technology · +3 more institutions
Abstract
An active cell membrane-camouflaged nanoparticle, owning to membrane antigens and membrane structure, can achieve special properties such as specific recognition, long blood circulation, and immune escaping. Herein, we reported a cancer cell membrane-cloaked nanoparticle system as a theranostic nanoplatform. The biomimetic nanoparticles (indocyanine green (ICG)-loaded and cancer cell membrane-coated nanoparticles, ICNPs) exhibit a core-shell nanostructure consisting of an ICG-polymeric core and cancer cell membrane shell. ICNPs demonstrated specific homologous targeting to cancer cells with good monodispersity, preferable photothermal response, and excellent fluorescence/photoacoustic (FL/PA) imaging…
Citation impact
- FWCI
- 30.27
- Percentile
- 100%
- References
- 41
Authors
13- ZCZe ChenCorresponding
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- PZPengfei Zhao
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- ZLZhenyu Luo
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, University of Chinese Academy of Sciences
- MZMingbin Zheng
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Guangdong Medical College, Guangdong Pharmaceutical University
- HTHao Tian
Guangdong Pharmaceutical University, Guangdong Medical College
Topics & keywords
- Photothermal therapy
- Nanotechnology
- Materials science
- Cancer
- Nanoparticle
- Modal
- Dual (grammatical number)
- Cancer therapy
Funding
- NNNational Natural Science Foundation of ChinaAwards: 81371679, 81401509, 81501580, 21375141, 81401520, 31571013
- CAChinese Academy of SciencesAward: YZ201439
- MOMinistry of Science and Technology of the People's Republic of ChinaAward: 2015DFH50230
- CPChina Postdoctoral Science FoundationAward: 2015M572386