The ChEMBL database in 2017

Gaulton, Anna; Hersey, Anne; Nowotka, Michał; Bento, A. Patrícia; Chambers, Jon; Méndez, David; Mutowo, Prudence; Atkinson, Francis; Bellis, Louisa J.; Cibrián–Uhalte, Elena; Davies, Mark; Dedman, Nathan; Karlsson, Anneli; Magariños, María Paula; Overington, John P.; Papadatos, George; Smit, Ines; Leach, Andrew R.

doi:10.1093/nar/gkw1074

articleNucleic Acids ResearchOct 31, 2016GOLD OA

The ChEMBL database in 2017

AGAnna Gaulton AHAnne Hersey MNMichał Nowotka APA. Patrícia Bento JCJon Chambers

European Bioinformatics Institute · Open Targets

PubMed

Indexed incrossrefdoajpubmed

Abstract

ChEMBL is an open large-scale bioactivity database (https://www.ebi.ac.uk/chembl), previously described in the 2012 and 2014 Nucleic Acids Research Database Issues. Since then, alongside the continued extraction of data from the medicinal chemistry literature, new sources of bioactivity data have also been added to the database. These include: deposited data sets from neglected disease screening; crop protection data; drug metabolism and disposition data and bioactivity data from patents. A number of improvements and new features have also been incorporated. These include the annotation of assays and targets using ontologies, the inclusion of targets and indications for clinical candidates, addition of…

Citation impact

2,394

total citations

FWCI: 164.01
Percentile: 100%
References: 56

Citations per year

Authors

18

Topics & keywords

Topics

Keywords

chEMBL
Biology
Database
Computer science
Bioinformatics
Drug discovery

No related works found for this paper.