Activatable Photosensitizers: Agents for Selective Photodynamic Therapy
Ewha Womans University · Bilkent University
Abstract
Recent developments in the design of bifunctional and activatable photosensitizers rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While systematic studies have uncovered new dyes that can serve as potential photosensitizers, the most promising results have come from studies aimed at gaining precise control over the location and rate of cytotoxic singlet oxygen generation. As a consequence, higher selectivities and efficiencies in photodynamic treatment protocols are now within reach. This feature article highlights the variety of approaches that have been pursued to improve photodynamic therapy and to transform simple photosensitizers into smarter theranostic agents.
Citation impact
- FWCI
- 23.62
- Percentile
- 100%
- References
- 82
Authors
4Topics & keywords
- Photodynamic therapy
- Singlet oxygen
- Photosensitizer
- Nanotechnology
- Bifunctional
- Materials science
- Sensitization
- Photochemistry