DeconvolutionLab2: An open-source software for deconvolution microscopy
École Polytechnique Fédérale de Lausanne
Indexed incrossrefpubmed
Abstract
Images in fluorescence microscopy are inherently blurred due to the limit of diffraction of light. The purpose of deconvolution microscopy is to compensate numerically for this degradation. Deconvolution is widely used to restore fine details of 3D biological samples. Unfortunately, dealing with deconvolution tools is not straightforward. Among others, end users have to select the appropriate algorithm, calibration and parametrization, while potentially facing demanding computational tasks. To make deconvolution more accessible, we have developed a practical platform for deconvolution microscopy called DeconvolutionLab. Freely distributed, DeconvolutionLab hosts standard algorithms for 3D microscopy…
Citation impact
630
total citations
- FWCI
- 56.79
- Percentile
- 100%
- References
- 62
Citations per year
Authors
9Topics & keywords
Topics
Keywords
- Deconvolution
- Microscopy
- Tikhonov regularization
- Blind deconvolution
- Computer science
- Algorithm
- Wiener deconvolution
- Inverse problem
No related works found for this paper.