reviewChemical ReviewsJan 13, 2017Closed access

Oxidative C–H/C–H Coupling Reactions between Two (Hetero)arenes

YYYudong YangJLJingbo LanJYJingsong You

Sichuan University

PubMed
Indexed incrossrefpubmed

Abstract

Transition metal-mediated C-H bond activation and functionalization represent one of the most straightforward and powerful tools in modern organic synthetic chemistry. Bi(hetero)aryls are privileged π-conjugated structural cores in biologically active molecules, organic functional materials, ligands, and organic synthetic intermediates. The oxidative C-H/C-H coupling reactions between two (hetero)arenes through 2-fold C-H activation offer a valuable opportunity for rapid assembly of diverse bi(hetero)aryls and further exploitation of their applications in pharmaceutical and material sciences. This review provides a comprehensive overview of the fundamentals and applications of transition…

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1,078
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Authors

3

Topics & keywords

Topics
Keywords
  • Chemistry
  • Chemoselectivity
  • Regioselectivity
  • Combinatorial chemistry
  • Conjugated system
  • Organic synthesis
  • Oxidative phosphorylation
  • Substrate (aquarium)
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