Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology

Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. In 2016, an estimated 95,270 new cases of colon cancer and approximately 39,220 cases of rectal cancer will occur. During the same year, an estimated 49,190 people will die of colon and rectal cancer combined. 1 Despite these high numbers, the incidence of colon and rectal cancers per 100,000 people decreased from NCCN Colon Cancer, Version 1.