reviewFrontiers in PharmacologyJan 18, 2017GOLD OA

Nanomaterials in Targeting Cancer Stem Cells for Cancer Therapy

Sun Yat-sen University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Cancer stem cells (CSCs) have been identified in almost all cancers and give rise to metastases and can also act as a reservoir of cancer cells that may cause a relapse after surgery, radiation, or chemotherapy. Thus they are obvious targets in therapeutic approaches and also a great challenge in cancer treatment. The threat presented by CSCs lies in their unlimited proliferative ability and multidrug resistance. These findings have necessitated an effective novel strategy to target CSCs for cancer treatment. Nanomaterials are on the route to providing novel methods in cancer therapies. Although, there have been a large number of excellent work in the field of targeted cancer therapy, it remains an open…

Citation impact

655
total citations
FWCI
47.75
Percentile
100%
References
148
Citations per year

Authors

4

Topics & keywords

Keywords
  • Cancer
  • Cancer stem cell
  • Medicine
  • Cancer therapy
  • Radiation therapy
  • Cancer research
  • Cancer cell
  • Targeted therapy
UN Sustainable Development Goals
  • Good health and well-being
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