reviewNeuroscience BulletinFeb 17, 2017HYBRID OA

An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options

AMAnne MasiMMMarilena M. DeMayoNGNick GlozierAJAdam J. Guastella

University of Sydney

PubMed
Indexed incrossrefpubmed

Abstract

Since the documented observations of Kanner in 1943, there has been great debate about the diagnoses, the sub-types, and the diagnostic threshold that relates to what is now known as autism spectrum disorder (ASD). Reflecting this complicated history, there has been continual refinement from DSM-III with 'Infantile Autism' to the current DSM-V diagnosis. The disorder is now widely accepted as a complex, pervasive, heterogeneous condition with multiple etiologies, sub-types, and developmental trajectories. Diagnosis remains based on observation of atypical behaviors, with criteria of persistent deficits in social communication and restricted and repetitive patterns of behavior. This review provides a broad…

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Authors

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Topics & keywords

Topics
Keywords
  • Autism spectrum disorder
  • Comorbidity
  • Etiology
  • Autism
  • Genetic heterogeneity
  • Medical diagnosis
  • Spectrum disorder
  • Clinical psychology
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