The Horizon of Materiobiology: A Perspective on Material-Guided Cell Behaviors and Tissue Engineering
East China University of Science and Technology · Queensland University of Technology
Abstract
Although the biological functions of cell and tissue can be regulated by biochemical factors (e.g., growth factors, hormones), the biophysical effects of materials on the regulation of biological activity are receiving more attention. In this Review, we systematically summarize the recent progress on how biomaterials with controllable properties (e.g., compositional/degradable dynamics, mechanical properties, 2D topography, and 3D geometry) can regulate cell behaviors (e.g., cell adhesion, spreading, proliferation, cell alignment, and the differentiation or self-maintenance of stem cells) and tissue/organ functions. How the biophysical features of materials influence tissue/organ regeneration have been…
Citation impact
- FWCI
- 24.66
- Percentile
- 100%
- References
- 417
Authors
3Topics & keywords
- Regeneration (biology)
- Tissue engineering
- Regenerative medicine
- Organism
- Cell biology
- Chemistry
- Multicellular organism
- Cell adhesion