reviewAnnals of NeurologyFeb 21, 2017Closed access

The gut microbiome in human neurological disease: A review

University of British Columbia · Canada's Michael Smith Genome Sciences Centre · +2 more institutions

PubMed
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Abstract

Almost half the cells and 1% of the unique genes found in our bodies are human, the rest are from microbes, predominantly bacteria, archaea, fungi, and viruses. These microorganisms collectively form the human microbiota, with most colonizing the gut. Recent technological advances, open access data libraries, and application of high-throughput sequencing have allowed these microbes to be identified and their contribution to neurological health to be examined. Emerging evidence links perturbations in the gut microbiota to neurological disease, including disease risk, activity, and progression. This review provides an overview of the recent advances in microbiome research in relation to neuro(auto)immune and…

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