Mindboggling morphometry of human brains

Mindboggle (http://mindboggle.info) is an open source brain morphometry platform that takes in preprocessed T1-weighted MRI data and outputs volume, surface, and tabular data containing label, feature, and shape information for further analysis. In this article, we document the software and demonstrate its use in studies of shape variation in healthy and diseased humans. The number of different shape measures and the size of the populations make this the largest and most detailed shape analysis of human brains ever conducted. Brain image morphometry shows great potential for providing much-needed biological markers for diagnosing, tracking, and predicting progression of mental health disorders. Very few…

• NI
  National Institutes of Health
• NI
  National Institute on Alcohol Abuse and Alcoholism

  Award: NCANDA-USA Consortium BD2K
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  National Institute of Mental Health

  Awards: U01 MH074813, 3U01MH092250-03S1, U01 supplement 3U01MH092250-03S1, 1U01MH108168-01, MH074813, 3R01MH092380-04S2, MH084029, R01 MH084029
• NI
  National Institute of Biomedical Imaging and Bioengineering

  Awards: 1R01EB020740-01A1, 1P41EB019936-01A1