reviewOncotargetFeb 25, 2017DIAMOND OA

The regulation of β-catenin activity and function in cancer: therapeutic opportunities

SSShuang ShangFHFang HuaZHZhuowei Hu

Chinese Academy of Medical Sciences & Peking Union Medical College

PubMed
Indexed incrossrefpubmed

Abstract

// Shuang Shang 1,* , Fang Hua 1,* and Zhuo-Wei Hu 1 1 Immunology and Cancer Pharmacology Group, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica; Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P.R. China * These authors have contributed equally to this work Correspondence to: Zhuo-Wei Hu, email: // Keywords : Wnt signaling, protein stability, subcellular localization, transcriptional regulation, cancer therapy Received : December 20, 2016 Accepted : February 15, 2017 Published : February 25, 2017 Abstract Wnt/β-catenin signaling is an evolutionarily conserved and versatile pathway that is known to be involved in…

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634
total citations
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20.41
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100%
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123
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Authors

3

Topics & keywords

Topics
Keywords
  • Wnt signaling pathway
  • Cancer research
  • Carcinogenesis
  • Cancer
  • Catenin
  • Biology
  • Cancer stem cell
  • Colorectal cancer
UN Sustainable Development Goals
  • Good health and well-being
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