A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures

The biological performance of artificial biomaterials is closely related to their structure characteristics. Cell adhesion, migration, proliferation, and differentiation are all strongly affected by the different scale structures of biomaterials. Silk fibroin (SF), extracted mainly from silkworms, has become a popular biomaterial due to its excellent biocompatibility, exceptional mechanical properties, tunable degradation, ease of processing, and sufficient supply. As a material with excellent processability, SF can be processed into various forms with different structures, including particulate, fiber, film, and three-dimensional (3D) porous scaffolds. This review discusses and summarizes the various…

• NS
  National Science Foundation
• NN
  National Natural Science Foundation of China

  Awards: 2016YFC1100100, 51373110
• GO
  Government of Jiangsu Province
• NS
  Natural Science Foundation of Jiangsu Province

  Award: BK20161253
• PA
  Priority Academic Program Development of Jiangsu Higher Education Institutions
• QP
  Qinglan Project of Jiangsu Province of China
• NK
  National Key Research and Development Program of China

  Award: 2016YFC1100100