Adiposity and cancer at major anatomical sites: umbrella review of the literature
Imperial College Healthcare NHS Trust · Imperial College London · +6 more institutions
Abstract
Objective To evaluate the strength and validity of the evidence for the association between adiposity and risk of developing or dying from cancer. Design Umbrella review of systematic reviews and meta-analyses. Data sources PubMed, Embase, Cochrane Database of Systematic Reviews, and manual screening of retrieved references. Eligibility criteria Systematic reviews or meta-analyses of observational studies that evaluated the association between indices of adiposity and risk of developing or dying from cancer. Data synthesis Primary analysis focused on cohort studies exploring associations for continuous measures of adiposity. The evidence was graded into strong, highly suggestive,…
Citation impact
- FWCI
- 33.56
- Percentile
- 100%
- References
- 111
Authors
8- MKMaria KyrgiouCorresponding
Imperial College Healthcare NHS Trust, Imperial College London, Queen Charlotte's and Chelsea Hospital, Hammersmith Hospital
- IKIlkka Kalliala
Imperial College London
- GMGeorgios Markozannes
University of Ioannina
- MJMarc J. Gunter
Centre International de Recherche sur le Cancer
- EPEvangelos Paraskevaidis
University of Ioannina
Topics & keywords
- Medicine
- Meta-analysis
- Endometrial cancer
- Cancer
- Internal medicine
- Oncology
- Body mass index
- Cohort study
- Good health and well-being
Funding
- GRGenesis Research TrustAward: P63522
- WCWorld Cancer Research Fund InternationalAward: 2014/1180
- CRCancer Research UK
- NINational Institute for Health and Care ResearchAward: P45272
- OCOvarian Cancer ActionAward: PS5827
- IEImperial Experimental Cancer Medicine Centre
- WCWorld Cancer Research FundAward: 2014/1180