Metal-Catalyzed Decarboxylative C–H Functionalization
Army Medical University · Chinese Academy of Sciences · +2 more institutions
Abstract
C–H bond activation and decarboxylation are two significant processes in organic synthesis. The combination of these processes provides a novel synthetic strategy, that is, decarboxylative C–H bond functionalization. Considerable attention has been focused on such an active research field. This review offers an overview of the utility of decarboxylative C–H bond functionalization in the synthesis of various organic compounds, such as styrenes, chalcones, biaryls, and heterocycles, covering most of the recent advances of the decarboxylative functionalization of Csp–H, Csp2–H, and Csp3–H bonds, as well as their scopes, limitations, practical applications, and synthetic potentials.
Citation impact
- FWCI
- 46.89
- Percentile
- 100%
- References
- 122
Authors
4- YWYe WeiCorresponding
Army Medical University, Chinese Academy of Sciences, Fujian Institute of Research on the Structure of Matter
- PHPeng Hu
Sun Yat-sen University, Chinese Academy of Sciences, Fujian Institute of Research on the Structure of Matter
- MZMin Zhang
Chinese Academy of Sciences, Fujian Institute of Research on the Structure of Matter
- WSWeiping Su
Chinese Academy of Sciences, Fujian Institute of Research on the Structure of Matter
Topics & keywords
- Surface modification
- Chemistry
- Decarboxylation
- Catalysis
- Combinatorial chemistry
- Organic synthesis
- Organic chemistry
Funding
- NNNational Natural Science Foundation of ChinaAwards: u1505242, 21302220, 21431008, 21332001
- SYSun Yat-sen University
- NSNatural Science Foundation of ChongqingAward: cstc2016jcyjA0008
- SKState Key Laboratory of Structural ChemistryAward: 20150009
- CICAS-SAFEA International Partnership Program for Creative Research Teams