Emerging concepts in sporadic cerebral amyloid angiopathy
Massachusetts General Hospital · Harvard University
Abstract
Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and a largely untreatable cause of intracerebral haemorrhage and contributor to age-related cognitive decline. The term 'cerebral amyloid angiopathy' now encompasses not only a specific cerebrovascular pathological finding, but also different clinical syndromes (both acute and progressive), brain parenchymal lesions seen on neuroimaging and a set of diagnostic criteria-the Boston criteria, which have resulted in increasingly detected disease during life. Over the past few years, it has become clear that, at the pathophysiological level, cerebral amyloid angiopathy appears to be in part a protein elimination failure angiopathy…
Citation impact
- FWCI
- 27.99
- Percentile
- 100%
- References
- 188
Authors
8- ACAndreas CharidimouCorresponding
Massachusetts General Hospital, Harvard University
- GBGrégoire Boulouis
Harvard University, Massachusetts General Hospital
- MEM. Edip Gurol
Harvard University, Massachusetts General Hospital
- CACenk Ayata
Harvard University, Massachusetts General Hospital
- BJBrian J. Bacskai
Harvard University, Massachusetts General Hospital
Topics & keywords
- Cerebral amyloid angiopathy
- Angiopathy
- Amyloidosis
- Amyloid (mycology)
- Medicine
- Neuroscience
- Pathology
- Psychology
- Good health and well-being