reviewChemical Society ReviewsJan 1, 2017Closed access

Fluorescent bioimaging of pH: from design to applications

JHJi-Ting HouWXWen Xiu RenKLKun LiJSJinho SeoASAmit Sharma

Korea University · The Seoul Institute · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Protons play crucial roles in many physiological and pathological processes, such as receptor-mediated signal transduction, ion transport, endocytosis, homeostasis, cell proliferation, and apoptosis. The urgent demand for pH imaging and measurement in biological systems has incited the development of fluorescent pH probes. Numerous fluorescent probes have been reported, but many lack the abilities needed for biological applications. Hence, the development of new pH probes with better biocompatibility, sensitivity, and site-specificity is still indispensable. This review highlights the recent trends in the development of fluorescent materials as essential tools for tracing pH variations in the biological…

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554
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FWCI
25.34
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100%
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51
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Authors

7

Topics & keywords

Keywords
  • Fluorescence
  • Chemistry
  • Nanotechnology
  • Materials science
  • Physics
  • Optics
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