Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity
Boston Children's Hospital · Howard Hughes Medical Institute · +2 more institutions
Abstract
Neuronal populations in specific hypothalamic sub-regions. Furthermore, we found food deprivation exhibited differential transcriptional effects among the different neuronal subtypes, suggesting functional specification of various neuronal subtypes. Thus, the work provides a comprehensive transcriptional perspective of adult hypothalamus, which serves as a valuable resource for dissecting cell-type-specific functions of this complex brain region.
Citation impact
- FWCI
- 24.67
- Percentile
- 100%
- References
- 48
Authors
4- RCRenchao ChenCorresponding
Boston Children's Hospital, Howard Hughes Medical Institute
- XWXiaoji Wu
Howard Hughes Medical Institute, Boston Children's Hospital
- LJLan Jiang
Howard Hughes Medical Institute, Boston Children's Hospital
- YZYi Zhang
Harvard University, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Boston Children's Hospital
Topics & keywords
- RNA-Seq
- Cell
- RNA
- Diversity (politics)
- Computational biology
- Biology
- Transcriptome
- Cell biology
- Zero hunger